1. 奈米藥物或基因治療輸送載體開發：開發基於生物材料之奈米載體應用於藥物輸送與基因治療輸送等領域。(Nanocarrier Development: Developing nanobiomaterial carriers for applications in drug delivery and gene delivery.)
2. 分子模擬與蛋白質結構預測：利用分子模擬與蛋白質結構預測技術開發功能性重組蛋白，應用於蛋白藥物或開發輸送載體。(Molecular simulation and protein structure prediction: Use molecular simulation and protein structure prediction to develop functional recombinant proteins for applications in protein drugs or development of delivery vectors.)
3. 重組蛋白設計與基因工程：設計功能性重組蛋白並利用基因工程技術生產、萃取與純化重組蛋白，並利用工程化奈米載體應用於生醫相關應用。(Recombinant protein design and genetic engineering: Design functional recombinant proteins and utilize genetic engineering technology to produce, extract and purify recombinant proteins. Development of engineered nanocarriers for biomedical applications.)
4. 腦癌分子生物機轉：研究腦癌細胞分子生物學機轉，並開發為潛在治療靶點。。(Molecular Biological Mechanism of Brain tumors: Study the molecular biological mechanism of brain tumor cells and develop potential therapeutic targets.)

1. Yu-Chi Pan, Ying-Tzu Chen, Hao-Han Pang, Chatchayapa Prayadrat, ShihChung Huang, Hung-Wei Yang. (2025) RNA aptamer-packaged virus-like particles for label-free, rapid, and on-site fluorescence detection of malachite green in aquatic products. Biosensors and Bioelectronics 228, 117796. 10.1016/j.bios.2025.117796.
2. Ying-Pei Hsu, Nan-Si Li, Hao-Han Pang, Yu-Chi Pan, Hung-Pei Tsai, HsiaoChien Chen, Ying-Tzu Chen, Chen-Hsun Weng, Shiao-Wei Kuo, Hung-Wei Yang. (2025) Lab-on-the-Needles: A Microneedle Patch-Based Mobile Unit for Highly Sensitive Ex Vivo and In Vivo Detection of Protein Biomarkers. ACS nano 19, 3249–3264. DOI: 10.1021/acsnano.4c11238. (Journal Cover)
3. Nan-Si Li, Ying-Pei Hsu, Hao-Han Pang, Sheng-Fan Wang, See-Tong Pang, Chih-Yen Lin, Rung-Ywan Tsai, Chiung-Yin Huang, Kuo-Chen Wei, Hung-Wei Yang. (2024) Lab-in-a-Vial Rapid Test for Internet of Things Imbedded Point-of-Healthcare Protein Biomarker Detections in Bodily Fluids. Small 20, 2470369. DOI: 10.1002/smll.202400878 (Journal Cover)
4. Hao-Han Pang, Nan-Si Li, Ying-Pei Hsu, Shin-Pon Ju, Guan-Da Syu, Pin-Xian Du, Chiung-Yin Huang, Kuo-Chen Wei, Hung-Wei Yang (2024) AI-Driven Design System for Fabrication of Inhalable Nanocatchers for Virus Capture and Neutralization. Advanced Healthcare Materials 13, 2302927. DOI: 10.1002/adhm.202302927. (Journal Cover)
5. Hao-Han Pang, Chiung-Yin Huang, Pin-Yuan Chen, Nan-Si Li, Ying-Pei Hsu, Jan-Kai Wu, Hsiu-Fang Fan, Kuo-Chen Wei*, and Hung-Wei Yang*. (2023) Bioengineered bacteriophage-like nanoparticles as RNAi therapeutics to enhance radiotherapy against glioblastomas. ACS Nano 17, 10407–10422. DOI: 10.1021/acsnano.3c01102. (Journal Cover)
6. Yi-Jyun Chen, Ying-Pei Hsu, You-Lin Tain, Nan-Si Li, Hao-Han Pang, ShiaoWei Kuo*, Hung-Wei Yang* (2022) Microneedle patches integrated with lateral flow cassettes for blood-free chronic kidney disease point-of-care testing during a pandemic. Biosensors and Bioelectronics 208, 114234. DOI: 10.1016/j.bios.2022.114234.
7. Wen-Hsuan Chen, Kai-Jie Yu, Jia-Wei Jhou, Hao-Han Pang, Wen-Hui Weng, Wen-Sou Lin*, and Hung-Wei Yang* (2021) Glucose/glutathione co-triggered tumour hypoxia relief and chemodynamic therapy to enhance photothermal therapy in bladder cancer. ACS Applied Bio Materials, 4, 10, 7485–7496. DOI: 10.1021/acsabm.1c00741.
8. Hao-Han Pang, Yong-Chen Ke, Nan-Si Li, Ying-Tzu Chen, Chiung-Yin Huang, Kuo-Chen Wei*, Hung-Wei Yang*. (2020) A new lateral flow plasmonic biosensor based on gold-viral biomineralized nanozyme for on-site intracellular glutathione detection to evaluate drug-resistance level. Biosensors and Bioelectronics 165, 112325. DOI: 10.1016/j.bios.2020.112325
9. Nan-Si Li, Ying-Tzu Chen, Ying-Pei Hsu, Hao-Han Pang, Chiung-Yin Huang, Yow-Ling Shiue, Kuo-Chen Wei*, Hung-Wei Yang* (2020) Mobile healthcare system based on the combination of lateral flow pad and smartphone for rapid detection of uric acid detection in whole blood. Biosensors and Bioelectronics 164, 112309. DOI: doi.org/10.1016/j.bios.2020.112309.
10. Ying-Pei Hsu, Hung-Wei Yang*, Nan-Si Li, Ying-Tzu Chen, Hao-Han Pang, and See-Tong Pang. (2020) Instrument-Free Detection of FXYD3 Using Vial-Based Immunosensor for Earlier and Faster Urothelial Carcinoma Diagnosis. ACS Sensors 5,928-935. DOI: 10.1021/acssensors.9b02013.
11. Ying-Pei Hsu, Nan-Si Li, Ying-Tzu Chen, Hao-Han Pang, Kuo-Chen Wei, HungWei Yang* (2020) A serological point-of-care test for Zika virus detection and infection surveillance using an enzyme-free vial immunosensor with a smartphone. Biosensors and Bioelectronics 151, 111960. Doi: 10.1016/j.bios.2019.111960.
12. Hao-Han Pang#, Chiung-Yin Huang#, Ya-Wen Chou, Chia-Jung Lin, Zi-Lin Zhou, Yow-Ling Shiue, Kuo-Chen Wei*, Hung-Wei Yang*. (2019) Bioengineering fluorescent virus-like particle/RNAi nanocomplexes act synergistically with temozolomide to eradicate brain tumors. Nanoscale, 11, 8102-8109. DOI: 10.1039/C9NR01247H.
13. Hao-Han Pang, Pin-Yuan Chen, Kuo-Chen Wei, Chiun-Wei Huang, Yow-Ling Shiue, Chiung-Yin Huang, Hung-Wei Yang (2019) Convection-enhanced delivery of a virus-like nanotherapeutic agent with dual-modal imaging for besiegement and eradication of brain tumors. Theranostics 9, 1752-1763. DOI: 10.7150/thno.30977 [Inside Front Cover].

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