龎浩翰 博士

基本資料 / Profiles

藥物研發中心龎浩翰助理研究員個人半身正裝照
龎浩翰 助理研究員
Hao-Han Pang, Assistant Research Fellow
藥物研發中心助理研究員
現職 / Job Title
 

藥物研發中心 助理研究員Assistant Research Fellow, CDRD

聯絡資訊 / Contact
 

信箱：hhpang@mail.cgust.edu.tw

分機：5264

ORCID：0000-0001-9071-9649 🔗

主要學歷 / Education
 

國立中山大學 生物醫學研究所 博士Ph.D., Institute of Biomedical Sciences, National Sun Yat-Sen University

經歷 / Experience
 
  • 長庚科技大學 藥物研發中心 助理研究員
  • 美國俄亥俄州立大學 訪問學者
  • 美國全國兒童醫院 博士後研究員
  • 國立成功大學 生物醫學工程學系 博士後研究員
  • 國立中山大學 醫學科技研究所 博士後研究員
研究專長 / Specialization
 

奈米生醫材料、基因治療與藥物輸送、分子模擬、基因工程、腦癌分子生物機轉Nano-biomaterials, Gene Therapy & Drug Delivery, Molecular Simulation, Genetic Engineering, Brain Tumor Molecular Mechanisms

實驗室成員 / Lab Members
 

研究助理：1 人 (Research Assistant)

實驗室位置 / Lab Location
 

位置：E棟4樓 藥物設計與劑型創新應用研究室Drug Design and Innovative Formulation Application Lab, Building E, 4F

研究方向 / Research Focus
 
  1. 奈米藥物或基因治療輸送載體開發：開發基於生物材料之奈米載體應用於藥物輸送與基因治療輸送等領域。(Nanocarrier Development: Developing nanobiomaterial carriers for applications in drug delivery and gene delivery.)
  2. 分子模擬與蛋白質結構預測：利用分子模擬與蛋白質結構預測技術開發功能性重組蛋白，應用於蛋白藥物或開發輸送載體。(Molecular Simulation & Protein Structure Prediction: Develop functional recombinant proteins for applications in protein drugs or delivery vectors.)
  3. 重組蛋白設計與基因工程：設計功能性重組蛋白並利用基因工程技術生產、萃取與純化重組蛋白，並利用工程化奈米載體應用於生醫相關應用。(Recombinant Protein Design & Genetic Engineering: Design and purify recombinant proteins via genetic engineering for biomedical applications.)
  4. 腦癌分子生物機轉：研究腦癌細胞分子生物學機轉，並開發為潛在治療靶點。(Molecular Biological Mechanism of Brain Tumors: Study molecular biological mechanisms of brain tumor cells to develop potential therapeutic targets.)
論文著作 (近五年內著作目錄) / Publications (Selected Papers)
 
  1. Pan, Yu-Chi; Chen, Ying-Tzu; Pang, Hao-Han; Prayadrat, Chatchayapa; Huang, ShihChung; Yang, Hung-Wei. (2025) RNA aptamer-packaged virus-like particles for label-free, rapid, and on-site fluorescence detection of malachite green in aquatic products. Biosensors and Bioelectronics 228, 117796. 10.1016/j.bios.2025.117796.
  2. Hsu, Ying-Pei; Li, Nan-Si; Pang, Hao-Han; Pan, Yu-Chi; Tsai, Hung-Pei; Chen, HsiaoChien; Chen, Ying-Tzu; Weng, Chen-Hsun; Kuo, Shiao-Wei; Yang, Hung-Wei. (2025) Lab-on-the-Needles: A Microneedle Patch-Based Mobile Unit for Highly Sensitive Ex Vivo and In Vivo Detection of Protein Biomarkers. ACS nano 19, 3249–3264. DOI: 10.1021/acsnano.4c11238. (Journal Cover)
  3. Li, Nan-Si; Hsu, Ying-Pei; Pang, Hao-Han; Wang, Sheng-Fan; Pang, See-Tong; Lin, Chih-Yen; Tsai, Rung-Ywan; Huang, Chiung-Yin; Wei, Kuo-Chen; Yang, Hung-Wei. (2024) Lab-in-a-Vial Rapid Test for Internet of Things Imbedded Point-of-Healthcare Protein Biomarker Detections in Bodily Fluids. Small 20, 2470369. DOI: 10.1002/smll.202400878 (Journal Cover)
  4. Pang, Hao-Han; Li, Nan-Si; Hsu, Ying-Pei; Ju, Shin-Pon; Syu, Guan-Da; Du, Pin-Xian; Huang, Chiung-Yin; Wei, Kuo-Chen; Yang, Hung-Wei (2024) AI-Driven Design System for Fabrication of Inhalable Nanocatchers for Virus Capture and Neutralization. Advanced Healthcare Materials 13, 2302927. DOI: 10.1002/adhm.202302927. (Journal Cover)
  5. Pang, Hao-Han; Chiung-Yin Huang; Pin-Yuan Chen; Nan-Si Li; Ying-Pei Hsu; Jan-Kai Wu; Hsiu-Fang Fan; Wei, Kuo-Chen*; and Yang, Hung-Wei*. (2023) Bioengineered bacteriophage-like nanoparticles as RNAi therapeutics to enhance radiotherapy against glioblastomas. ACS Nano 17, 10407–10422. DOI: 10.1021/acsnano.3c01102. (Journal Cover)
  6. Chen, Yi-Jyun; Hsu, Ying-Pei; Tain, You-Lin; Li, Nan-Si; Pang, Hao-Han; Kuo, ShiaoWei*; Yang, Hung-Wei* (2022) Microneedle patches integrated with lateral flow cassettes for blood-free chronic kidney disease point-of-care testing during a pandemic. Biosensors and Bioelectronics 208, 114234. DOI: 10.1016/j.bios.2022.114234.
  7. Chen, Wen-Hsuan; Yu, Kai-Jie; Jhou, Jia-Wei; Pang, Hao-Han; Weng, Wen-Hui; Lin, Wen-Sou*; and Yang, Hung-Wei* (2021) Glucose/glutathione co-triggered tumour hypoxia relief and chemodynamic therapy to enhance photothermal therapy in bladder cancer. ACS Applied Bio Materials, 4, 10, 7485–7496. DOI: 10.1021/acsabm.1c00741.
  8. Pang, Hao-Han; Ke, Yong-Chen; Li, Nan-Si; Chen, Ying-Tzu; Huang, Chiung-Yin; Wei, Kuo-Chen*; Yang, Hung-Wei*. (2020) A new lateral flow plasmonic biosensor based on gold-viral biomineralized nanozyme for on-site intracellular glutathione detection to evaluate drug-resistance level. Biosensors and Bioelectronics 165, 112325. DOI: 10.1016/j.bios.2020.112325
  9. Li, Nan-Si; Chen, Ying-Tzu; Hsu, Ying-Pei; Pang, Hao-Han; Huang, Chiung-Yin; Shiue, Yow-Ling; Wei, Kuo-Chen*; Yang, Hung-Wei* (2020) Mobile healthcare system based on the combination of lateral flow pad and smartphone for rapid detection of uric acid detection in whole blood. Biosensors and Bioelectronics 164, 112309. DOI: doi.org/10.1016/j.bios.2020.112309.
  10. Hsu, Ying-Pei; Yang, Hung-Wei*; Li, Nan-Si; Chen, Ying-Tzu; Pang, Hao-Han; and Pang, See-Tong. (2020) Instrument-Free Detection of FXYD3 Using Vial-Based Immunosensor for Earlier and Faster Urothelial Carcinoma Diagnosis. ACS Sensors 5, 928-935. DOI: 10.1021/acssensors.9b02013.
  11. Hsu, Ying-Pei; Li, Nan-Si; Chen, Ying-Tzu; Pang, Hao-Han; Wei, Kuo-Chen; Yang, Hung-Wei* (2020) A serological point-of-care test for Zika virus detection and infection surveillance using an enzyme-free vial immunosensor with a smartphone. Biosensors and Bioelectronics 151, 111960. Doi: 10.1016/j.bios.2019.111960.
  12. Pang, Hao-Han#; Huang, Chiung-Yin#; Chou, Ya-Wen; Lin, Chia-Jung; Zhou, Zi-Lin; Shiue, Yow-Ling; Wei, Kuo-Chen*; Yang, Hung-Wei* (2019) Bioengineering fluorescent virus-like particle/RNAi nanocomplexes act synergistically with temozolomide to eradicate brain tumors. Nanoscale, 11, 8102-8109. DOI: 10.1039/C9NR01247H.
  13. Pang, Hao-Han; Chen, Pin-Yuan; Wei, Kuo-Chen; Huang, Chiun-Wei; Shiue, Yow-Ling; Huang, Chiung-Yin; Yang, Hung-Wei (2019) Convection-enhanced delivery of a virus-like nanotherapeutic agent with dual-modal imaging for besiegement and eradication of brain tumors. Theranostics 9, 1752-1763. DOI: 10.7150/thno.30977 [Inside Front Cover].
龎浩翰博士第一篇期刊封面 (Journal Cover) 龎浩翰博士第二篇期刊封面 (Journal Cover) 龎浩翰博士第三篇期刊封面 (Journal Cover) 龎浩翰博士第四篇期刊封面 (Journal Cover) 龎浩翰博士第五篇內頁封面 (Inside Front Cover)
個人學術研究 / Academic Research
 

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